A DNA-METHYLATION-DRIVEN GENES BASED PROGNOSTIC SIGNATURE REVEALS IMMUNE MICROENVIRONMENT IN PANCREATIC CANCER

A DNA-Methylation-Driven Genes Based Prognostic Signature Reveals Immune Microenvironment in Pancreatic Cancer

Pancreatic cancer (PACA), which is characterized by an immunosuppressive nature, remains one of the deadliest malignancies worldwide.Aberrant DNA methylation (DNAm) reportedly influences tumor immune microenvironment.Here, we evaluated the role of DNA methylation driven genes (MDGs) in PACA through integrative analyses of epigenomic, transcriptomic

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ISO 9001 IN ORGANIZATIONS: INFLUENCING FACTORS AND BENEFITS

The aim of this study is to identify and classify potential and verified benefits of implementing quality read more management systems according to ISO 9001 standard and to give an overview on how certain positive or negatyve factors manifest in the adherence to ISO 9001 hydrangea red sensation in practice.The paper classifies the major identified

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OVARIAN AGING AND INFERTILITY TREATMENT

Background.Due to changes in the socio-economic environment the first pregnancy is being more often postponed to advanced age; an increasing number of women seek medical help for infertility in their late thirties.Degenerative processes in the ovary start as early as after 35 years of age.When the woman is over 38, the signs of cubs foam finger hor

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